• Latest
  • Trending

Nanoparticles-based improved cancer drug could be in the offing

January 4, 2021
Public Bytes TV: Revolutionizing Indian News with Multilingual Power

Public Bytes TV: Revolutionizing Indian News with Multilingual Power

June 7, 2025
Lotus Derma Botanics Enters the Skincare Arena

Lotus Derma Botanics Enters the Skincare Arena

May 28, 2025
Pahia: A Mohali-Based Startup Empowering Street Vendors with Technology

Pahia: A Mohali-Based Startup Empowering Street Vendors with Technology

May 23, 2025
Kingston Powers Tomorrow: Enabling the Future of AI with High-Performance Solutions at COMPUTEX 2025

Kingston Powers Tomorrow: Enabling the Future of AI with High-Performance Solutions at COMPUTEX 2025

May 22, 2025
Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment

Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment

May 22, 2025
House of Jewels Rebrands and Launches Online: Vinaya Verma’s Side Hustle Now a Sparkling Digital Brand

House of Jewels Rebrands and Launches Online: Vinaya Verma’s Side Hustle Now a Sparkling Digital Brand

May 21, 2025
Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions

Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions

May 14, 2025
Rice Over Bread: How Lenexis Foodworks Captured India’s Chinese Food Market

Rice Over Bread: How Lenexis Foodworks Captured India’s Chinese Food Market

May 14, 2025
MarkSimpl Technologies: Redefining Trademark Protection with AI-Powered Intelligence

MarkSimpl Technologies: Redefining Trademark Protection with AI-Powered Intelligence

April 9, 2025
Lotus Herbals Launches Multimedia Campaign for Safe Sun Ultra Rx Sunscreen Serum SPF 60+

Lotus Herbals Launches Multimedia Campaign for Safe Sun Ultra Rx Sunscreen Serum SPF 60+

April 3, 2025
Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!

Upgrade Your Setup this Republic Day with Kingston’s Exclusive Offer!

January 21, 2025
Vairat Marathi Film Title Song Released Featuring Bollywood Actor Shantanu Bhamare, Giri S Raj & Balasaheb Bangar!

Vairat Marathi Film Title Song Released Featuring Bollywood Actor Shantanu Bhamare, Giri S Raj & Balasaheb Bangar!

December 2, 2024
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News
Sunday, June 29, 2025
  • Login
Bihar Live
  • Home
  • Bihar
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
    • Music
  • Lifestyle
    • Health & Fitness
    • Fashion
    • Travel
    • Food
      • Recipes
  • Tech
    • App News
    • Gadgets
  • Auto
  • Others
    • Sports
    • Agriculture
    • Science
    • Astrology
    • Finance/Money
    • Press Release
No Result
View All Result
Bihar Live
No Result
View All Result

Nanoparticles-based improved cancer drug could be in the offing

Bihar Live by Bihar Live
January 4, 2021
in Health & Fitness
0
Share on FacebookShare on Twitter

New Delhi (India Science Wire): A promising method for cancer treatment by using nanoparticles, with fewer side effects and more effectiveness has been developed by a multi-institutional team from the Regional Centre for Biotechnology (Haryana), Amity University (Haryana), and National Institute of Immunology (New Delhi). In this method, nanoparticles that deliver anti-cancer drugs have been developed. The results from animal studies are promising and further research is in progress for the method to be rolled out for treatment.

Docetaxel is a drug that is commonly used to treat various types of cancer including breast, colon, and lung cancer. A formulation of the drug that is approved by the United States Food and Drug Administration (FDA) is being used all over the world. However, some components in this formulation cause harmful side effects such as liver damage and difficulty in breathing. Hence, the research team sought to develop a better alternative.

YOU MAY ALSO LIKE

Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment

Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions

“Docetaxel is not soluble in water, and it has to be dissolved in a chemical mixture such as polysorbate-80 and alcohol to make it more soluble. This suspension is approved by the FDA, and it is commonly used worldwide including in India. Besides being potent, the drug also produces severe toxic effects in the body. So, we have developed a method that reduces the toxicity of the drug and improves its efficacy” says Dr. Avinash Bajaj, one of the corresponding authors of the study.

The team has developed nanoparticles called nanomicelles for the study. These nanomicelles are extremely small in size ranging from 10 to 100 nanometers and they serve as efficient systems through which the drugs can be delivered. This drug delivery system predominantly targets only the cancerous cells, but not the normal healthy cells.

Speaking about this, Dr. Bajaj said, “The tumor tissues have leaky blood vessels. The nanomicelles that carry docetaxel get trapped in these tumor tissues and the drug gets accumulated there. Compared to the formulation that is currently used, our formulation has shown relatively higher accumulation of docetaxel in the tumor tissues than the healthy tissues which indicates its safety and efficacy”.

The research was carried out extensively on various laboratory animals such as mice, rabbits, and monkeys. They used mice as a breast cancer model and found that the nanomicelle based drug delivery system reduced the size of the tumor in mice without producing toxic effects.

“We have been granted approval for conducting our research on 16 monkeys apart from mice, rats, and rabbits. In preclinical studies with mice, we have observed that these nanomicelles retard tumor growth. Compared to FDA-approved formulation, these nanomicelles also showed an increased rate of survivability” adds Dr. Bajaj.

The team is now working on developing nanomicelles that can carry multiple drugs instead of one drug which would increase the overall efficacy of the treatment method. About this Dr. Bajaj said, “Cancer patients are undergoing different chemotherapy cycles with different drugs. Now, we are planning to develop a nanoparticle through which a combination of drugs can be delivered instead of a single drug so that several pathways in the body can be targeted at the same time. In the future, we are also planning to work on immunotherapy along with chemotherapy”.

The study was recently published in the journal Angewandte Chemie. The research team consisted of Vedagopuram Sreekanth, Animesh Kar, Sandeep Kumar, Sanjay Pal, Poonam Yadav, Yamini Sharma, Varsha Komalla, Harsh Sharma, Radhey Shyam, Ravi D Sharma, Arnab Mukhopadhyay, Sagar Sengupta, Ujjaini Dasgupta, and Avinash Bajaj.(India Science Wire)

Tags: cancer drugNanoparticles
ShareTweetSharePinSendShareSend
Previous Post

National Atomic Timescale Inaugurated

Next Post

Assam Rifles Public School, Shillong becomes the first Khelo India Sports School from North-East

Bihar Live

Bihar Live

Related Posts

Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment
Health & Fitness

Tvara Superfood Launches India’s First Daily Seed Cycling Blends for Female Hormonal and Chakra Nourishment

by Bihar Live
May 22, 2025
Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions
Health & Fitness

Aveya IVF & Fertility Center: Pioneering Accessible Parenthood with Fertility Solutions

by Bihar Live
May 14, 2025
Dr Sunita Dube along with 21 Lakh Doctors Supports Tribunal Health law raised in Parliament by MP
Health & Fitness

Dr Sunita Dube along with 21 Lakh Doctors Supports Tribunal Health law raised in Parliament by MP

by Bihar Live
December 12, 2023
“Empowering Women Through Innovative Healthcare: Dr. Monika Agarwal, Leading Cosmetic Gynaecologist and Laparoscopic Surgeon in Ghaziabad”
Health & Fitness

“Empowering Women Through Innovative Healthcare: Dr. Monika Agarwal, Leading Cosmetic Gynaecologist and Laparoscopic Surgeon in Ghaziabad”

by Bihar Live
September 4, 2023
A Coworker’s Heroic CPR and AED Deployment Saves a 52-Year-Old Man from Cardiac Arrest
Health & Fitness

A Coworker’s Heroic CPR and AED Deployment Saves a 52-Year-Old Man from Cardiac Arrest

by Bihar Live
August 8, 2023
Next Post

Assam Rifles Public School, Shillong becomes the first Khelo India Sports School from North-East

40th Indian scientific expedition to Antarctica launched

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Search

No Result
View All Result

Recent News

Public Bytes TV: Revolutionizing Indian News with Multilingual Power

Public Bytes TV: Revolutionizing Indian News with Multilingual Power

June 7, 2025
Lotus Derma Botanics Enters the Skincare Arena

Lotus Derma Botanics Enters the Skincare Arena

May 28, 2025
Pahia: A Mohali-Based Startup Empowering Street Vendors with Technology

Pahia: A Mohali-Based Startup Empowering Street Vendors with Technology

May 23, 2025
Bihar Live

Bihar Live, digital news and story platform bring you the news, articles, stories, and opinions on the latest happenings worldwide covering various sectors like nation, politics, and governance, social sector, review, foreign affairs, defence and security, latest review, lifestyle, entertainment, sports, technology, auto sectors, education, business and start-ups updates, Agriculture, Science, finance, money, food, and culture, etc.

Recent News

  • Public Bytes TV: Revolutionizing Indian News with Multilingual Power
  • Lotus Derma Botanics Enters the Skincare Arena
  • Pahia: A Mohali-Based Startup Empowering Street Vendors with Technology

Follow us on Google News

June 2025
M T W T F S S
 1
2345678
9101112131415
16171819202122
23242526272829
30  
« May    
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Follow on Google News

© 2022 Bihar Live - Design and Developed by Brand Maker RD.

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 Bihar Live - Design and Developed by Brand Maker RD.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In